Comparison of D2 vs D3 Lymph Node Dissection for Right Colon Cancer (RICON)

G.V. Bondar Republican Cancer Center

Status: Active, not recruiting

Conditions: Colon Cancer

Treatments: Procedure: Right Hemicolectomy with D3 lymph node dissection; Procedure: Right Hemicolectomy with D2 lymph node dissection

Study type: Interventional

Funder types: Other

Identifiers

NCT03200834

0001

Details and patient eligibility

About

Comparing different method of surgical technique D2 lymph node dissection vs D3 for right colon cancer.

Enrollment: 239 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Agreement of the patient to participate in trial
2. Colon cancer (only adenocarcinoma )
3. The tumor located between the cecum and the right 1/3 of transverse colon
4. Tumors T3,Т4а,b N0-2 (II-III stages)
5. Tolerance of chemotherapy
6. ECOG 0-2

Exclusion criteria

1. Patients with distant metastases
2. Tumors T1-2 (I stage)
3. Complications of tumor (perforation and full bowel obstruction)
4. Previous radiotherapy or chemotherapy
5. Synchronous or metachronous tumors
6. Women during Pregnancy or breast feeding period

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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239 participants in 2 patient groups

D2 lymph node dissection for right colon cancer

Active Comparator group

Description:

Hemicolectomy for right colon cancer with D2 lymph node dissection

Treatment:

Procedure: Right Hemicolectomy with D2 lymph node dissection

D3 lymph node dissection for right colon cancer

Experimental group

Description:

Hemicolectomy for right colon cancer with D3 lymph node dissection

Treatment:

Procedure: Right Hemicolectomy with D3 lymph node dissection