Comparison of Diagnostic Accuracy for Predicting Histology of Colorectal Lesions

Shanghai Jiao Tong University School of Medicine

Status: Completed

Conditions: Colorectal Neoplasms

Study type: Observational

Funder types: Other

Identifiers

NCT01521091

rjxhnk01

Details and patient eligibility

About

Chromoendoscopy (indigo carmine or acetic acid) and Narrow Band Imaging (NBI) could make accurate evaluation in predicting of invasive depth of colorectal neoplasia. NBI could be the first choice.

Full description

To compare the diagnostic accuracy of chromoendoscopy indigo carmine or acetic acid and NBI for differentiating neoplastic from non-neoplastic colorectal lesions, differentiating adenomas from carcinomas, and differentiating early carcinomas from invasive ones.

Included colorectal lesions consecutively distribute in a 1:1 ratio to 2 groups.

Enrollment: 565 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Consecutive patients with more than one lesion ≧ 6mm .

Exclusion criteria

• Patients with chronic inflammatory bowel disease, advanced cancer, insufficient bowel preparation, familial adenomatous polyposis (FAP)
• Lesions ≦ 5mm and submucosal tumor (SMT).