Comparison of Different Protocols of Fluid Therapy in Severe Preeclamptic Patients Under Spinal Anesthesia

Assiut University

Status and phase: Unknown; Early Phase 1

Conditions: Hypotension Drug-Induced

Treatments: Drug: Lactated Ringer

Study type: Interventional

Funder types: Other

Identifiers

NCT03478618

haemodynamics in preeclampsia

Details and patient eligibility

About

To compare the effect of two different protocol of fluid therapy in sever preeclamptic patients under spinal anesthesia : Hemodynamic and kidney function .

Enrollment: 60 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• more than 36 weeks gestation
• singleton pregnant women planned for elective caesarian section

Exclusion criteria

• patient refusal.
• psychiatric disorders.
• parturient <36 weeks gestation, twins, abnormal cardiotocography (CTG) tracing.
• absolute contraindications for spinal anesthesia (patients refusal, raised intracranial pressure, hypovolemic states, abnormal coagulopathy).

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Group R

Active Comparator group

Description:

30 patients will receive 15ml/kg/h lactated Ringer (LR) intraoperative.

Treatment:

Drug: Lactated Ringer

Group L

Active Comparator group

Description:

30 patients will receive 30ml/kg/h lactated Ringer (LR) intraoperative.

Treatment:

Drug: Lactated Ringer