Comparison of DisCoVisc and Hydroxypropylmethylcellulose 2%

University of Sao Paulo

Status and phase: Completed; Phase 4

Conditions: Corneal Edema; Intraocular Pressure

Treatments: Drug: Hyaluronic Acid and hydroxypropylmethylcellulose

Study type: Interventional

Funder types: Other

Identifiers

NCT01387620

USP - 0111 - 09

Details and patient eligibility

About

This prospective study was performed to compare two ophthalmic viscosurgical devices, DisCoVisc (hyaluronic acid 1.6% - chondroitin sulfate 4.0%) and hydroxypropylmethylcellulose 2% in terms of their overall clinical performance during phacoemulsification.

Enrollment: 39 patients

Sex: All

Ages: 50 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Bilateral age-related cataract
• Grade 1-3 lens opacities classification system (LOCS III)
• Pupil dilatation greater than 7.0 mm

Exclusion criteria

• Black, brunescent, traumatic or subluxated cataract
• Corneal endothelial disease (endothelial cell count less than 2.000 cells/mm3)
• Glaucoma, uveitis
• Previous ocular surgery

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Quadruple Blind