Comparison of Effects of Eggshell Derived Nano Hydroxyapatite and Hydroxyapatite in Management of Periodontal Intrabony Defects

Dr R Viswa Chandra

Status: Completed

Conditions: Periodontal Intrabony Defects; Bone Regeneration

Treatments: Other: Eggshell derived nano hydroxyapatite; Other: Hydroxyapatite

Study type: Interventional

Funder types: Other

Identifiers

NCT07160101

SVSIDS/PERIO/1/2022

Details and patient eligibility

About

The aim of the study is to evaluate osseous regenerative efficacy of eggshell derived nanohydroxyapatite in comparison with hydroxyapatite The test group includes patients with intrabony defects where flap surgery will be performed & Eggshell derived nano hydroxyapatite (ESnHA) is placed.

Full description

Experimental : Main treatment group Eggshell derived nano hydroxyapatite is placed into defect site Comparator : In patients allocated to control group, only Hydroxyapatite is placed.

Enrollment: 28 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Presence of Two-walled or three-walled intrabony defects & Probing pocket depths (PPD) of >5mm after initial therapy Systemically healthy male and female patients of age >18 years

Exclusion criteria

Medically compromised patients Pregnant women, Heavy smokers, and Patients who underwent radiotherapy or chemotherapy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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28 participants in 2 patient groups

Test group Eggshell derived nano hydroxyapatite

Experimental group

Description:

In Test group after flap reflection \& degranulation, bone graft i.e Eggshell derived nano hydroxyapatite is placed into defect.

Treatment:

Other: Eggshell derived nano hydroxyapatite

Control group

Active Comparator group

Description:

In Control group, after flap reflection \& debridment bone graft i.e Hydroxyapatite is placed into defect.

Treatment:

Other: Hydroxyapatite