Comparison of Efficiency of Closed Kinetic Chain Exercises Versus Proprioceptive Exercises Patient With Hemophilia

Bahçeşehir University

Status: Enrolling

Conditions: Hemophilia B; Hemophilia A

Treatments: Other: Closed Chain Exercise Group; Other: Proprioceptive Exercise Group

Study type: Interventional

Funder types: Other

Identifiers

NCT05879549

E-74555795-050.01.04-689576

Details and patient eligibility

About

Hemophilia is a bleeding disorder caused by a deficiency of clotting factors in the blood. Muscle and joint bleeding are frequently observed in patients with hemophilia. Lower extremity bleeding can adversely affect balance, gait, and proprioception. The goal of this study; To compare the effectiveness of closed kinetic chain exercises and proprioceptive exercises on balance, proprioception and gait parameters in adolescent and young hemophilic individuals with lower extremity joint involvement.

The main question it aims to answer is:

Are the effects of closed kinetic chain exercises and proprioceptive exercises different on balance and walking in hemophilic individuals?

Enrollment: 63 estimated patients

Sex: Male

Ages: 13 to 25 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Having been diagnosed with Hemophilia A and Hemophilia B
• Having a blood factor level below 5%,
• Between 13-25 years old
• History of bleeding to the lower extremity and target joint
• Total lower extremity Hemophilia joint health score ≥3
• Using prophylaxis

Exclusion criteria

• Having undergone lower extremity surgery in the last 6 months
• Having a Body Mass Index over 30 kg/m2
• Have an inhibitor
• Using a walking aid

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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63 participants in 3 patient groups

Closed Chain Exercise Group

Experimental group

Description:

Closed kinetic chain exercises will be given under the supervision of a physiotherapist, 2 sessions a week for 12 weeks.

Treatment:

Other: Closed Chain Exercise Group

Proprioceptive Exercise Group

Experimental group

Description:

Proprioceptive exercises will be given under the supervision of a physiotherapist, 2 sessions a week for 12 weeks.

Treatment:

Other: Proprioceptive Exercise Group

Control Group

No Intervention group

Description:

No intervention will be applied.