Comparison of Embryo Transfer in Egg Donation Recipients With Transvaginal and Transabdominal Ultrasound

IVI Madrid

Status and phase: Terminated; Early Phase 1

Conditions: Infertility

Treatments: Procedure: Transabdominal ultrasound-guided embryo transfer; Procedure: Transvaginal ultrasound-guided embryo transfer

Study type: Interventional

Funder types: Other

Identifiers

NCT01805505

MAD-EH-01-2012-01

Details and patient eligibility

About

Transabdominal ultrasound guidance is the golden standard for embryo transfers. Transvaginal ultrasound guidance was proposed recently to provide better visualization and reduce patient discomfort as embryo transfer can be performed with an empty bladder in this case. The purpose of this study is to determine whether there are any differences between transvaginal and transabdominal ultrasound-guided embryo transfer in terms of ease of use, patient satisfaction, and treatment outcome.

Enrollment: 346 patients

Sex: Female

Ages: 18 to 49 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing oocyte donation treatment with transfer of 2 embryos on day 3

Exclusion criteria

• Submucous or >3 cm intramural fibroids
• Turner syndrome
• Black recipients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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346 participants in 2 patient groups

Transvaginal ultrasound-guided embryo transfer

Experimental group

Description:

Transvaginal ultrasound-guided transfer of two day-3 embryos

Treatment:

Procedure: Transvaginal ultrasound-guided embryo transfer

Transabdominal ultrasound-guided embryo transfer

Active Comparator group

Description:

Transabdominal ultrasound-guided transfer of two day-3 embryos

Treatment:

Procedure: Transabdominal ultrasound-guided embryo transfer