Comparison of Endometrial Protein Profile in Spontaneous Versus Stimulated Menstrual Cycles in Poor Responders

University Medical Centre Ljubljana

Status: Completed

Conditions: Proteome

Treatments: Other: use of gonadotropins

Study type: Interventional

Funder types: Other

Identifiers

NCT06804174

(0120-319/2021/3)

Details and patient eligibility

About

Evaluation of endometrial protein profile in spontaneous and stimulated menstrual cycles

Enrollment: 15 patients

Sex: Female

Ages: 18 to 43 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Primary infertility
2. Poor ovarian response

Exclusion criteria

1. Normal or high ovarian response to gonadotropin stimulation
2. Menstrual cycle disorders
3. Severe male cause of infertility
4. Preimplantation genetic testing
5. Pathological findings of the uterus (fibroids, endometrial polyps, adenomyosis) and fallopian tubes (distal occlusion of one or both fallopian tubes with hydrosalpinx).

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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15 participants in 1 patient group

Poor responder women as per POSEIDON criteria

Experimental group

Treatment:

Other: use of gonadotropins