Comparison of Erector Spinae Plane Block and Intravenous Analgesic in Nefrectomy

Kocaeli University

Status: Completed

Conditions: Nephrectomy; Regional Anesthesia Morbidity

Treatments: Procedure: erector spinea plane block administered preoperative open nephrectomy; Procedure: intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg

Study type: Interventional

Funder types: Other

Identifiers

NCT04686890

KIA 2020/96

Details and patient eligibility

About

The efficacy of erector spinae plane block versus intravenous analgesics compared relate to the morphine consumptions

Full description

Patients undergoing elective nefrectomy were enrolled. Patients divided into two groups with a sealed envelope technique to ESP+ pca morphine group or iv analgesic + pca morphine group. All patients will premedicated. then esp will applied to one group before surgery at the preoperative care unit by the same anesthesiologist. The other group will receive intravenous tramadol 1 mg/kg + NSAID 1 ampule + parol 10 mg/ kg + ondansetron 4 mg bolus. İntravenous morphine pca with a concentration of 0.5 mg/cc were applied. And administered 1 mg boluses every 15 minutes lock time and 4 hour limit as 4 mg arranged. An anesthesia nurse who is responsible of all pcas' in the hospital was recorded the variables of these patients in the service

Enrollment: 46 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:18-65 years age

• ASA I-II
• undergoing elective nephrectomy

Exclusion Criteria:- ASA>3

• heart disease
• pregnancy
• lung disease
• scoliosis
• bleeding disorder
• infection at the manipulation side

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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46 participants in 3 patient groups

postoperative opiod (morphine) consumption

Active Comparator group

Description:

patient-controlled analgesia (15 minutes. lock time, 2 ml bolus= total 1 mg morphine intravenously, limited to maximum 4 bolus / per hour )

Treatment:

Procedure: erector spinea plane block administered preoperative open nephrectomy

Procedure: intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg

peroperative continuous opioid (remifentanil) consumption

Active Comparator group

Description:

continuous remifentanil infusion was given during the whole procedure

Treatment:

Procedure: erector spinea plane block administered preoperative open nephrectomy

Procedure: intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg

postoperative numerated rating scale

Active Comparator group

Description:

at the 1, 3, 6, 12 and 24 th hour postoperatively - numerated rating scale score was evaluated and recoded as 0= no pain (better), 10: unbearable pain (worse)

Treatment:

Procedure: erector spinea plane block administered preoperative open nephrectomy

Procedure: intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg