Comparison of Gd-EOB-DTPA-enhanced MRI and Contrast-enhanced Ultrasound for Measuring Tumor Size of Solitary Hepatocellular Carcinoma ≤ 5cm:A Retrospective Study

Anhui Medical University

Status

Completed

Conditions

HCC - Hepatocellular Carcinoma

Treatments

Radiation: ceus

Study type

Observational

Funder types

Other

Identifiers

NCT06437457

2023-RE-117

Details and patient eligibility

About

Knowing the tumor size before operation is of great significance to the choice of treatment methods of surgeons and the prognosis of patients. In this study, two commonly used imaging methods( CE-MRI/CEUS) were selected to measure and compare the tumor size before operation, in order to determine which measurement method is more accurate.

Full description

A total of 194 patients who met the inclusion criteria from January 2019 through May 2024 were included. Taken pathological results as the gold standard, Paired T-test and Bland-Altman analisis were conducted to assess the correlation and mean absolute error between the measured tumor sizes obtained from CE-MRI/CEUS and pathological results.

Enrollment

194 patients

Sex

All

Volunteers

No Healthy Volunteers

Inclusion criteria

had no anti-HCC therapy before imaging examinations.
at least had one examination of Gd-EOB-DTPA-enhanced MRI and CEUS 2 weeks before surgery and confirmed as one single HCC.
If the patient had both imaging tests, the time interval between two examinations was less than 1 weeks.
both radiological and pathological results recorded the maximum tumor diameter.

Exclusion criteria

had anti-HCC therapy before imaging examinations.
had no examination of Gd-EOB-DTPA-enhanced MRI or CEUS 2 weeks before surgery .
had no radiological or pathological results recorded the maximum tumor diameter.