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Comparison of Gonioscopy With Cirrus and Visante (ASOCT)

W

Wills Eye

Status

Completed

Conditions

Narrow Angles
Angle Closure Glaucoma
Open Angle Glaucoma

Study type

Observational

Funder types

Other

Identifiers

NCT01895686
11-080E

Details and patient eligibility

About

The aim of this study is to analyze similarities and evaluate interchangeability of Visante and Cirrus OCT (optical coherent tomography)and to compare agreement between gonioscopy and the two systems for evaluation of anterior segment parameters.

Full description

All participants underwent routine ophthalmic examination by their physician. Three independent examiners performed gonioscopy using Spaeth Gonioscopic Grading System. Findings were recorded independently along with risk assessment of angle being closed as: high, medium, and low or no risk. Patient information was not available to doctor during gonioscopy. One eye of each patient was imaged using both Visante and Cirrus OCT. Imaging was performed under scotopic and photopic conditions and obtained from horizontal (3:00 and 9:00 o'clock) and vertical (6:00 and 12:00 o'clock) meridians. The same experienced independent examiner performed all Cirrus measurements. Visante was performed by 3 trained technicians using same protocol.

OCT images were exported and masked to be evaluated for presence of open or closed anterior chamber angle. Masked images were presented with no other patient information available to two examiners with glaucoma training working together to score on basis of iridocorneal angle as, closed (0 degree), high possibility (10 degree), medium risk (20 degree), and low or no risk (> 30 degree).

Enrollment

54 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

• 18 years of age and older with open angle, narrow angle and angle closure

Exclusion criteria

• All lasers or intraocular surgery (cataract, glaucoma, retina, cornea)

Trial design

54 participants in 3 patient groups

Open angle glaucoma
Description:
patients diagnosed with open angle glaucoma
Narrow angle
Description:
patients diagnosed with narrow angles
Angle Closure Glaucoma
Description:
patients diagnosed with angle closure glaucoma

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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