Comparison of Hemodynamic Changes With Morphine Versus Esmolol During Induction of Anaesthesia

Pakistan Navy Station Shifa Hospital

Status and phase: Completed; Phase 2; Phase 1

Conditions: Intubation Complication

Treatments: Drug: Intravenous morphine

Study type: Interventional

Funder types: Other

Identifiers

NCT06065956

433/8/22

Details and patient eligibility

About

Comparing hemodynamic changes with morphine versus esmolol as an adjuvant agent during induction of Anaesthesia

Full description

Comparing hemodynamic profile of patients during induction of General Anesthesia with intravenous morphine as an adjuvant drug versus Intravenous esmolol as an adjuvant agent,My aim is to study which drug has superior hemodynamic profile in terms of hemodynamic stability of patient requiring General Anesthesia.

Enrollment: 110 patients

Sex: All

Ages: 25 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA 2 patients presenting for elective surgery.

Exclusion criteria

• Patients having major cardiac disease.
• Metastatic disease.
• Pregnant females.
• Those unwilling to be part of study.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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110 participants in 2 patient groups

Morphine group

Experimental group

Description:

Half of participants will be comprising of morphine group

Treatment:

Drug: Intravenous morphine

Esmolol group

Experimental group

Description:

Half of participants will be comprising of esmolol group

Treatment:

Drug: Intravenous morphine