Comparison of Heparin Types; Efficacy and Safety

McMaster University

Status and phase: Completed; Phase 4

Conditions: Coronary Artery Disease

Treatments: Drug: Hepalean Heparin; Drug: PPC Heparin

Study type: Interventional

Funder types: Other

Identifiers

NCT01343381

CANNeCTIN

Details and patient eligibility

About

Heparin, a blood thinner, is used routinely in Open-heart surgery. Do different brands of this drug have differing clinical effects despite both having exactly the same regulation and marketing specifications?

Enrollment: 21 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• will be undergoing cardiopulmonary bypass for coronary artery disease
• has provided written informed consent

Exclusion criteria

• Allergy or intolerance to Heparin

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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21 participants in 2 patient groups

Hepalean Heparin

Active Comparator group

Treatment:

Drug: Hepalean Heparin

PPC Heparin

Active Comparator group

Treatment:

Drug: PPC Heparin