Comparison of Hypotension After Spinal Anesthesia With Hyperbaric Vs Isobaric Bupivacaine in Elective Cesarean After Colloid Preloading.

Liaquat National Hospital & Medical College

Status and phase: Not yet enrolling; Phase 2

Conditions: Hypotension After Spinal Anesthesia

Treatments: Drug: Spinal anesthesia with hyperbaric bupivacaine; Drug: Spinal anesthesia with isobaric bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT07416084

1327-2026-LNH-ERC

Details and patient eligibility

About

To assess the hemodynamic difference after spinal anesthesia with hyperbaric bupivacaine and isobaric bupivacaine in elective cesarean section

Enrollment: 60 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA II parturient with normal pregnancy Parturients undergoing elective cesarean section under spinal anesthesia Parturient refusing normal trial of labor, planned for ELLSCS under spinal anesthesia

Exclusion criteria

• Patient refusal Parturient with known drug allergy to local anesthetics Parturients undergoing emergency cesarean section Spinal anesthesia converted to general anesthesia.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Hyperbaric bupivacaine

Active Comparator group

Description:

Hyperbaric bupivacaine used for spinal anesthesia

Treatment:

Drug: Spinal anesthesia with hyperbaric bupivacaine

Isobaric bupivacaine

Active Comparator group

Description:

Isobaric bupivacaine used for spinal anesthesia

Treatment:

Drug: Spinal anesthesia with isobaric bupivacaine