Comparison of Hypotension During Spinal Anaesthesia for C-section

Rawalpindi Medical University

Status: Completed

Conditions: Hypotension; Cesarean Section; Aortocaval Compression

Study type: Observational

Funder types: Other

Identifiers

NCT05427968

2021-4711-17843

Details and patient eligibility

About

Maternal hypotension during C section has been reported due to aortocaval compression (ACC) by full term uterus in supine position. This study aimed at reporting the effect of left tilt on maternal hemodynamics.

Full description

C-section is usually done in either general anesthesia or regional (epidural or spinal) anesthesia. The choice lies with the mother. In spinal anesthesia the anaesthetic agent is injected into the subarachnoid space. Hypotension in supine position that is associated with full term gravid uterus has been explained by compression of inferior venacava (IVF) and aorta. This aortocaval compression (ACC) can also cause hypotension during C- section after spinal block.

The aim of our study was to study the effect of left tilt on systolic (SBP) and diastolic blood pressure (DBP), heart rate and the frequency of phenylephrine used to maintain the blood pressure in normal range.

Enrollment: 38 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants ≥ 18 years, undergoing Elective Caesarean Section for term singleton pregnancy, ASA I/II, were included after their consent for the participation of the study.

Exclusion criteria

• Participants with co-morbidities (Hypertension, diabetes mellitus, cardiovascular or cerebrovascular disease and a history of coagulation disorders), any contraindication to spinal anesthesia, with multiple pregnancy, pre-eclampsia, obesity (body mass index > 30 kg.m2), intrauterine growth were excluded from the study.

Trial design

38 participants in 2 patient groups

Supine group

Description:

Spinal anaesthesia was administered in sitting position and then supine position was maintained.

Left tilt group

Description:

Spinal anesthesia was administered in sitting position was then maintained on supine position until full anesthetic effect (motor and sensory loss) and then table was tilted 15 degrees to the left.