Comparison of Individual Culture and Group Culture of Preimplantation Embryos in Human IVF Treatments (GroupCulture)

Semmelweis University

Status: Completed

Conditions: Other Complications Associated With Artificial Fertilization

Treatments: Other: individual embryo culture or group culture

Study type: Observational

Funder types: Other

Identifiers

NCT01774006

SemmelweisU-001

Details and patient eligibility

About

Prospective randomized comparison of two widely used in vitro culture system in human IVF treatments. In vitro fertilized oocytes and embryos are cultured in individual culture media droplets using conventional petridish or in group culture using WOW (well of the well) petridish.

Primary outcome: implantation and pregnancy rates Secondary outcome: fertilization rate and embryo quality

Enrollment: 532 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Infertile patients entering in vitro fertilization treatment
• at least 1 oocyte collected

Exclusion criteria

• no oocytes collected

Trial design

532 participants in 2 patient groups

Group culture

Description:

Embryos cultured in groups of 2-10

Treatment:

Other: individual embryo culture or group culture

Individual culture

Description:

Embryos cultured individually

Treatment:

Other: individual embryo culture or group culture