Comparison of Intubation With Nerve Block and With Sedation in Awake Patients

Tehran University of Medical Sciences

Status and phase: Unknown; Phase 3

Conditions: Intubation Complication

Treatments: Drug: Nerve block with Lidocain; Drug: Fentanyl; Drug: Midazolam

Study type: Interventional

Funder types: Other

Identifiers

NCT01768377

130-1928

Details and patient eligibility

About

The purpose of this study is to compare intubation with nerve block with intubation with sedation in awake patients in terms of efficacy, ease, and the rate of complications and physician satisfaction

Enrollment: 70 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Candidate for intubation with methods other than RSI
• Age>= 18 years
• Patient or patient's guardian's consent

Exclusion criteria

• Need for RSI or crash intubation
• Allergy to Lidocain in block group
• Allergy to opioid drugs in sedation group
• Allergy to midazolam in either group

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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70 participants in 2 patient groups

Intubation with sedation

Active Comparator group

Description:

Sedation with midazolam and analgesia with fentanyl

Treatment:

Drug: Midazolam

Drug: Fentanyl

Intubation with Nerve block

Experimental group

Description:

Laryngeal plus supraglottic plus intratracheal nerve block plus sedation with midazolam

Treatment:

Drug: Midazolam

Drug: Nerve block with Lidocain