Comparison of Laryngeal Mask Airway (LMA®) and Tracheal Tube in Modified Radical Mastectomy on Breast Cancer (LMATBBC)

Nanjing Medical University

Status and phase: Completed; Phase 4

Conditions: Breast Cancer

Treatments: Device: Endotracheal tube; Device: LMA®

Study type: Interventional

Funder types: Other

Identifiers

NCT00638599

NMU075451

NMU-2579-7FW

Details and patient eligibility

About

Airway management in anesthesia is critical to guarantee appropriate treatment of possible respiratory complications and successful operative practice. LMA® is an alternative to tracheal tube in some surgeries like as mastectomy on breast cancer. Given no need using muscular relaxants in mastectomy, the investigators hypothesized that LMA® would be a superior manner in airway management in radical modified mastectomy on breast cancer than the tracheal tube, and the LMA® might produce less influence on patients' circulatory homeostasis, and easier to be placed before operation.

Enrollment: 200 patients

Sex: Female

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Chinese
• Diagnosed breast cancer
• Undergoing modified radical mastectomy
• Agreed to participate the study with informed contract.

Exclusion criteria

• Organic dysfunction
• Long-lasting post-anesthetic care unit(PACU) staying.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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200 participants in 2 patient groups

1

Experimental group

Description:

LMA® is placed after anesthesia induction till the end of operation

Treatment:

Device: LMA®

2

Active Comparator group

Description:

Standard tracheal tube is inserted after anesthesia induction till the end of operation

Treatment:

Device: Endotracheal tube