Comparison of LASER Therapy and Desensitizing Agents in Dentinal Hypersensitivity

Kemia Gul

Status: Not yet enrolling

Conditions: Dentinal Hypersensitivity

Treatments: Device: Low Level Laser Therapy; Drug: Glutaraldehyde-Based Desensetizing Agent

Study type: Interventional

Funder types: Other

Identifiers

NCT06759454

208-ERB/024

Details and patient eligibility

About

This study evaluates the effectiveness of laser therapy versus desensitizing agents in reducing pain among participants with dentinal hypersensitivity conducted in Saidu College of Dentistry. Pain will be measured at baseline, immediately post-treatment, one week, and three months using the Visual Analog Scale (VAS)

Full description

This study examines dentinal hypersensitivity treatment modalities, including laser therapy and desensitizing agents. The study is conducted in compliance with regional ethical guidelines

Enrollment: 172 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Participants aged 18-50 years with a preoperative VAS score of ≥2 for dentinal hypersensitivity.
• Participants with sensitivity due to gingival recession, cervical abrasion, or enamel erosion.
• Participants with good systemic health.
• Minimum of two hypersensitive teeth present in two different quadrants.

Exclusion criteria

• Teeth with caries, defective restorations, or cervical defects > 2 mm (may affect sensitivity measurements).
• Periodontal surgery or deep periodontal pockets (> 6 mm) within the past three months (potential influence on periodontal health and sensitivity).
• Participants using desensitizing toothpaste within the past three months (could interfere with study outcomes).
• Presence of gross oral pathology or systemic diseases (e.g., eating disorders, chronic diseases, uncontrolled metabolic conditions) (may alter oral health status).
• Pregnant or lactating women (hormonal changes can influence oral health).

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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172 participants in 2 patient groups

Arm 1 (Desensitizing Agent)

Active Comparator group

Description:

A glutaraldehyde-based desensitizing agent applied to affected teeth for 30 seconds, air-dried, with post-application instructions

Treatment:

Drug: Glutaraldehyde-Based Desensetizing Agent

Arm 2 (Laser Therapy)

Experimental group

Description:

Diode laser set to 100 mW in continuous wave mode, applied to specific areas of affected teeth for three minutes

Treatment:

Device: Low Level Laser Therapy