Comparison of Low and Normal Flow Anesthesia in Robotic Assisted Radical Prostatectomy

Ankara City Hospital

Status: Not yet enrolling

Conditions: Low Flow Anesthesia; Normal Flow Anesthesia; Robotic Surgery

Treatments: Procedure: robotic assisted radical prostatectomy

Study type: Observational

Funder types: Other

Identifiers

NCT05517551

E1-22-2755

Details and patient eligibility

About

Robot-assisted laparoscopic radical prostatectomy has gained increasing popularity compared to open radical prostatectomy with its advantages such as low blood loss, reduced blood transfusion rate, low complication rate, and shortened hospital stay. Since robot-assisted laparoscopic radical prostatectomy should be performed in the limited retroperitoneal area, insufflation of the abdomen with carbon dioxide (CO2) (pneumoperitoneum) and steep Trendelenburg position are required to provide better surgical vision.

Low-flow anesthesia warms and moistens the inhaled gases, creating a more physiological breathing atmosphere during anesthesia. In addition, it provides cost advantage by reducing inhalation agent consumption and reduces atmospheric pollution. Studies show that long-term minimal flow anesthesia is safe and advantageous for non-laparoscopic surgery.

The aim of this study is to compare low-flow (1L/min) with normal flow (3lt/min) desflurane anesthesia in terms of hemodynamic and respiratory parameters, inhalation agent consumption and soda lime consumption for robotic assisted laparoscopic radical prostatectomy surgery.

The secondary aim of the study is to compare the effects of low-flow and normal-flow anesthesia in the steep trendelenburg position (45°) used for robotically assisted laparoscopic radical prostatectomy.

Enrollment: 68 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ASA I-II risk group

Exclusion criteria

• ASA III, IV, V,
• concomitant serious cardiac, respiratory, hepatic, renal disturbance,
• mental status disorder and hearing problem,
• anxiety and depression and/or other psychiatric disorders,
• patient's refusal

Trial design

68 participants in 2 patient groups

normal flow anesthesia

Description:

A fresh gas flow of 3 L/min will be applied continuously

Treatment:

Procedure: robotic assisted radical prostatectomy

low flow anesthesia

Description:

A fresh gas flow of 3 L/min will be applied for the first 20 minutes after intubation , and then it will be reduced to 1 L/min.

Treatment:

Procedure: robotic assisted radical prostatectomy