Comparison of Low GI and High GI Potatoes in Relation to Satiety (POSAT)

Anne Birgitte Raben

Status

Completed

Conditions

Obesity

Treatments

Other: Low glycaemic potato

Other: High glycaemic potato

Study type

Interventional

Funder types

Other

Identifiers

NCT03512509

B344

Details and patient eligibility

About

The study is a single-blind, randomised crossover study, investigating how a high glycaemic potato affects satiety in humans compared to a low glycaemic potato. This is done to shed further light on the discussion about whether potatoes with a high glycaemic index increases the risk of overweight and obesity and thus indirectly type 2 diabetes and cardiovascular disease.

Full description

The POSAT study follows a single-blinded randomized crossover design. Each subject will have two separate intervention days with at least a six-day washout period in between. On the two intervention days the subjects will be randomized into receiving a breakfast containing isocaloric amounts of either low or high GI potatoes. VAS will be measured 5 minutes before the meal, immediately after the meal is consumed and in intervals of 30 minutes thereafter until 2,5 hours after the initial meal. After this the subjects will be served a standardized homogenous ad libitum meal. The amount of food consumed will be registered. The subjects will be asked to fast for 8-10 hours prior to the trial days and abstain from vigorous physical activity and alcohol consumption for 2 days prior to each trial day. The trial will be conducted over a total of 8 days with 5-6 study subjects pr. trial day. The trial days will be spread out over a total of 2 weeks to allow for a 1-week washout period between trial days for each subject.

Enrollment

22 patients

Sex

Male

Ages

18 to 40 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Healthy men
Body mass index (BMI) 18-27 kg/m2
Age 18-40 years
Signed informed consent
Able to eat 500 grams of potato for breakfast

Exclusion criteria

Chronic diseases as diabetes, cardiovascular diseases or other chronic metabolic diseases, which could affect the results.
Use of daily prescription medicine (mild analgesics and antihistamines are allowed).
Use of medicine or dietary supplements that can affect ones appetite one month before the start of the study.
Smoking or have been smoking or using any nicotine products (gum or e-cigarette) within the last 3 months. Irregular smoking is allowed.
Elite athletes defined as doing >10 hours of strenuous physical activity per week.
Participation in other clinical studies <1 month before or during the study.
Inability, physically or psychologically, to comply with the procedures required by the study protocol. Judged by the investigators.
Any food allergies.
Weight change of ±3 kg from screening to the trial has been conducted.
Inability to complete the trial within 3 months after screening.
Unable to fast 8-10 hours before the trial days.