Comparison of Morphine and Fentanyl/Midazolam in Intensive Care Unit

Clínica de Los Andes IPS

Status: Completed

Conditions: Respiratory Failure

Treatments: Drug: Morphine infusion; Drug: Fentanyl and Midazolam infusion

Study type: Interventional

Funder types: Other

Identifiers

NCT01602640

ANDES001

Details and patient eligibility

About

Hypothesis: Morphine infusion decreases time to mechanical ventilation weaning and extubation, as compared to the combination of fentanyl and midazolam in critically-ill patients.

Enrollment: 90 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults admitted to ICU requiring mechanical ventilation Informed consent

Exclusion criteria

• Less than 18 years old
• Consent denial

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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90 participants in 2 patient groups

Morphine

Experimental group

Treatment:

Drug: Morphine infusion

Fentanyl and Midazolam

Active Comparator group

Description:

Control

Treatment:

Drug: Fentanyl and Midazolam infusion