Comparison of Nipple-areolar Complex Sensation According to Incision Types in Nipple-sparing Mastectomy

Yonsei University Health System (YUHS)

Status: Completed

Conditions: Breast Cancer; Nipple Sparing Mastectomy

Treatments: Biological: Nipple sparing mastecomy with different incision placements

Study type: Observational

Funder types: Other

Identifiers

NCT05917834

3-2019-0235

Details and patient eligibility

About

This study aims to assess nipple areolar complex sensation after nipple sparing mastectomy and compare the results according to different incisional approaches; specifically, inframammary fold (IMF) versus peri-areolar/radial. One-hundred-and-five post NSM patients from Oct 2019 to Nov 2021 have been recruited prospectively and evaluated for NAC sensory. A total of 97 patients (IMF 65 and peri-areolar/radial 32) were included in the analyses for comparison during follow up from 24 to 48 months after surgery. It was hypothesized that patients with IMF would have better outcomes for NAC senroy.

Enrollment: 105 patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Females who are older than 18
2. Patients who underwent nipple sparing mastectomy in Gangnam Severance Hospital

Exclusion criteria

1. Loss or excision of NAC due to post-surgical necrosis
2. Diagnosis of other conditions that may interfere with cutaneous sensation

Trial design

105 participants in 2 patient groups

Imframammary

Description:

Imframammary- NSM using imframammary incision

Treatment:

Biological: Nipple sparing mastecomy with different incision placements

Radial/Peri-areolar

Description:

Radial/Peri-areolar- NSM using Radial/Peri-areolar incision

Treatment:

Biological: Nipple sparing mastecomy with different incision placements