Comparison of Once Daily Versus 8 Hour Dosing of Gentamicin for the Treatment of Intrapartum Chorioamnionitis

Stanford University

Status: Completed

Conditions: Chorioamnionitis

Treatments: Drug: gentamicin

Study type: Interventional

Funder types: Other

Identifiers

NCT00185991

80104

Details and patient eligibility

About

To compare once daily versus 8 hour dosing of gentamicin for the treatment of chorioamnionitis.

Enrollment: 126 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• clinical diagnosis of chorioamnionitis

Exclusion criteria

• maternal renal disease, intrauterine fetal death, allergy to gentamicin

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Triple Blind

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126 participants in 2 patient groups

Once daily Gentamicin

Active Comparator group

Treatment:

Drug: gentamicin

Every eight hour Gentamicin

Active Comparator group

Treatment:

Drug: gentamicin