Comparison of Onset of Neuromuscular Blockade With Electromyographic and Acceleromyographic Monitoring

Mayo Clinic

Status

Completed

Conditions

Neuromuscular Blockade

Treatments

Device: Train of four measurement

Study type

Observational

Funder types

Other

Identifiers

NCT05120999

21-007425

Details and patient eligibility

About

The purpose of this research is to use 2 devices to compare the difference in the amount of time it takes for each device to register complete muscle relaxation after the muscle relaxing medication is given. The comparison will be made by using electromyographic (EMG), such as TetraGraph, and acceloromyographic (AMG), such as TOFScan, monitors at the time of insertion of breathing tube.

Enrollment

100 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients willing to participate and provide an informed consent.
Patients undergoing elective surgical procedures that require use of NMBA agents (rocuronium) administered intraoperatively.

Exclusion criteria

Patients with disorders, such as stroke, carpal tunnel syndrome, broken wrist with nerve damage, Dupuytren contracture, or any similar wrist injury.
Patients with systemic neuromuscular diseases such as myasthenia gravis.
Patients with significant organ dysfunction that can significantly affect pharmacokinetics of neuromuscular blocking and reversal agents; i.e., severe renal impairment or end-stage liver disease.
Patients having surgery that would involve prepping the arm into the sterile field.
Patients receiving a rapid sequence induction.