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Comparison of Outcomes Between Open Wedge High Tibial Osteotomy and Double Level Osteotomy in Antromedial Knee Arthritis With Extra Articular Deformity

A

Assiut University

Status

Not yet enrolling

Conditions

Knee Osteoarthritis

Treatments

Procedure: Open Wedge High Tibial Osteotomy
Procedure: Double Level Osteotomy

Study type

Interventional

Funder types

Other

Identifiers

NCT06135454
Knee Osteoarthritis

Details and patient eligibility

About

To compare the radiographic and clinical outcomes of varus osteoarthritic knees treated with an open-wedge high tibial osteotomy (OWHTO) alone or with a double-level osteotomy (DLO). It was hypothesized that treatment with DLO would prevent the joint line obliquity (JLO) , optimize post-operative limb alignment and provide better clinical and radiological outcomes after surgery than medial opening-wedge high tibial osteotomy (OWHTO) alone for patients with medial compartment osteoarthritis.

Full description

Osteoarthritis is a degenerative joint disease characterized by erosion of the articular cartilage, hypertrophy of the bone at the margins and subchondral sclerosis(1). Osteoarthritis of the knee is a common problem causing significant knee pain and disability. Medial compartment osteoarthritis is predisposed to be varus deformity of the knee(2). High tibial osteotomy (HTO) is a well-established method for treatment of medial Uni compartmental-knee osteoarthritis and correction of varus deformity(3).Double level osteotomy recently used as another method for treatment this problem to improve outcomes and decrease complication(4).

Enrollment

44 estimated patients

Sex

All

Ages

40 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients that are indicated for surgery for medial compartment osteoarthritis only (medial joint line tenderness, varus tibiofemoral malalignment) with classification of Kellgren Lawrence grade (1/2/3)
  • Age between 40 _ 60 years
  • No associated bony fractures or deformities
  • No associated ligamentous functional instability
  • Varus more than or equal 15 degrees

Exclusion criteria

  • Age younger than 40 or older than 60 years
  • Secondary Arthritis (Inflammatory arthritis, post-traumatic osteoarthritis, active knee infection)
  • Lateral Compartment OA or patellofemoral OA

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

44 participants in 2 patient groups

Open Wedge High Tibial Osteotomy
Experimental group
Treatment:
Procedure: Open Wedge High Tibial Osteotomy
Double Level Osteotomy
Experimental group
Treatment:
Procedure: Double Level Osteotomy
Procedure: Open Wedge High Tibial Osteotomy

Trial contacts and locations

0

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Central trial contact

Abd Elgawad Mohamed Abd Elgawad, Resident; Mohamed Kamal Abd Elnasser, Assistant professor

Data sourced from clinicaltrials.gov

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