Comparison of Outcomes Between Warshaw and Kimura Techniques for Spleen-preserving Minimally Invasive Distal Pancreatectomy

Zhejiang University

Status: Completed

Conditions: Spleen Preservation; Distal Pancreatectomy; Postpancreatectomy Hemorrhage

Treatments: Procedure: Splenic vessels preservation

Study type: Observational

Funder types: Other

Identifiers

NCT06084975

SP-MIDP

Details and patient eligibility

About

Spleen-persevering distal pancreatectomy (SP-DP) has been widely advocated as a routine procedure for benign or low-grade malignant tumors in the pancreatic body and tail, especially with a minimally invasive approach. Spleen preservation can be accomplished with Kimura technique (KT) or Warshaw technique (WT) Both of the two techniques were proved to be feasible and efficient. However, the perioperative outcomes and long-term benefits between patients with KT and WT in spleen-persevering minimally invasive distal pancreatectomy (SP-MIDP) remains controversial.

Several small series have reported a slightly higher prevalence of postpancreatectomy hemorrhage (PPH) in patients who undergo KT than those undergo WT. The exposure of splenic vessels to erosive pancreatic juice and the preservation of splenic vessels itself may explain the higher chance of PPH in KT. Larger volume studies are warranted to confirm this finding and to clarify the clinical significance. This study compared the perioperative outcomes between the two spleen-preserving techniques, with a focus on parameters relating to perioperative patient safety. Especially, the incidence and clinical relevance of PPH in SP-MIDP were evaluated.

Enrollment: 314 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• pathological diagnosis of benign or low-grade malignant pancreas tumors.

Exclusion criteria

• incomplete medical records,
• history of previous splenectomy,
• high-grade malignant pancreas tumors,
• conversion to open DP (ODP).

Trial design

314 participants in 2 patient groups

Kimura technique (KT)

Description:

Spleen preservation is accomplished by sparing the splenic vessels.

Treatment:

Procedure: Splenic vessels preservation

Warshaw technique (WT)

Description:

Spleen preservation is accomplished by sacrificing the splenic vessels and maintaining vascularity through the preserved short gastric and left gastroepiploic vessels.