Comparison of Pantoprazole and Ranitidine in Dyspepsia

Akdeniz University

Status and phase

Completed

Phase 4

Conditions

Dyspepsia

Treatments

Drug: Ranitidine

Drug: Pantoprazole

Study type

Interventional

Funder types

Other

Identifiers

NCT01737840

160

Details and patient eligibility

About

The H0 hypothesis of the study is there is no difference between pantoprazole and ranitidine in treating patients presented with dyspepsia to the emergency department.

The H1 hypothesis is there is difference between pantoprazole and ranitidine in treating patients presented with dyspepsia to the emergency department.

Full description

Dyspepsia is one of the common complaints in emergency department. Proton pomp inhibitors, H2 receptor blockers and anti-acids are common drugs for treating dyspepsia in emergency department. However there is no study in the emergency department comparing the effectiveness of these drugs. So the investigators planned this study which drug is effective in these patients in order to provide a cost-effective treatment in dyspeptic patients.

Enrollment

66 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Epigastric pain
Older than 18 years old

Exclusion criteria

Diagnosed as cholecystitis, pancreatitis, myocardial infarction, etc.. at the end of the emergency deparment evaluation period.
Pregnancy
Patients with unstable vital signs
Patients used anti-acid, H2 receptor blockers and proton pomp inhibitors in the last one hour.
Allergy to H2 receptor blockers and proton pomp inhibitors.
Patients denied to give inform consent and who are illiterate