Comparison of Physical Activity Regimens as Treatments for Obstructive Sleep Apnea

University of South Carolina

Status and phase: Completed; Phase 2; Phase 1

Conditions: Obstructive Sleep Apnea

Treatments: Behavioral: moderate-intensity aerobic and resistance training; Behavioral: low-intensity stretching

Study type: Interventional

Funder types: Other

Identifiers

NCT00956423

1R36CD000695-01

Details and patient eligibility

About

The purpose of this study is to compare the efficacy of two different physical activity regimens as complementary or alternative treatment options for the treatment of obstructive sleep apnea. A secondary purpose of the study is to examine the effects of these activity regimens on various health consequences of obstructive sleep apnea, including blood pressure, systemic inflammation, and daytime functioning.

Enrollment: 43 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• moderate-intensity obstructive sleep apnea (AHI >= 15)
• sedentary status

Exclusion criteria

• current treatment for obstructive sleep apnea (CPAP, oral devices, etc.)
• significant cardiovascular, pulmonary, or metabolic disease
• uncontrolled hypertension
• inability to exercise (e.g., musculoskeletal, neuromuscular, orthopedic problems)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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43 participants in 2 patient groups

moderate-intensity exercise training

Experimental group

Treatment:

Behavioral: moderate-intensity aerobic and resistance training

low-intensity stretching

Active Comparator group

Treatment:

Behavioral: low-intensity stretching