Comparison of Post-Operative Analgesia After Percutaneous Nephrolithotomy.

Armed Forces Institute of Urology, Rawalpindi

Status and phase: Completed; Phase 4

Conditions: Postoperative Pain; Pain

Treatments: Drug: paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.; Drug: Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg.

Study type: Interventional

Funder types: Other

Identifiers

NCT04835116

AFIU Rawalpindi

Details and patient eligibility

About

The rationale of this study was to compare the efficacy of peri-tract bupivacaine infiltration with intravenous post-operative analgesia following PCNL in reference to the context with the previous studies so that we can adopt the better technique to curtail the post-operative pain.

Full description

The rationale of this study was to compare the efficacy of peri-tract bupivacaine infiltration with intravenous postoperative analgesia following PCNL in reference to the context with the previous studies so that we can adopt the better technique to curtail the post-operative pain.

Enrollment: 68 patients

Sex: All

Ages: 12 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• all patients undergoing PCNL
• age from 12-65 years
• normal renal functions
• no history of chronic pain
• ASA I, II & III
• Both genders

Exclusion criteria

• history of local anaesthesia allergy
• Redo PCNL
• Multiple punctures during PCNL
• Excessive intra-operative bleeding
• Diabetes mellitus
• Coagulopathy
• Mental disorder
• ASA IV & V
• Active urinary tract infection.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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68 participants in 2 patient groups

Local Anesthesia

Other group

Description:

Group A patients received peri tract local anaesthesia infiltration with 0.25% Bupivacaine.

Treatment:

Drug: Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg.

Drug: paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.

Intravenous Analgesics

Other group

Description:

Group B patients received postoperative intravenous analgesia.

Treatment:

Drug: Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg.

Drug: paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.