Comparison of Postoperative Analgesic Efficacy of the Erector Spina Plane Block and Quadratus Lumborum Block in Open Nephrectomy: a Prospective Randomized Clinical Study

Kocaeli University

Status: Enrolling

Conditions: Renal Cell Carcinoma

Treatments: Procedure: postopeartive controlled anlagesia with morphine; Procedure: preoperative remifentanil consumption

Study type: Interventional

Funder types: Other

Identifiers

NCT05810571

KAEK / 12bl.01

Details and patient eligibility

About

patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block, and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continuous remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Full description

patients who will undergo elective open nephrectomy will be divided into three groups; the control (PCA), the erector spina plane block and the quadratus lumborum block. After standard anesthesia induction and monitorization then Bispectral index monitoring will be applied to all patients. Anesthesia will be maintained using sevoflurane in a mixture of oxygen and air. Continious remifentanil infusion will be used for analgesia. Then patient's numeric rating scales and morphine pca consumptions will be recorded for one day.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA 1-3
• open nephrectomy elective patients
• BMI<35

Exclusion criteria

• ASA 4-5-6
• Laparoscopic nephrectomy
• infection at the block side
• coagulation disorder
• BMI>35

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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60 participants in 3 patient groups, including a placebo group

patient controlled analgesia

Placebo Comparator group

Description:

this group of patients received no block, received only postoperative patient-controlled analgesia with morphine

Treatment:

Procedure: preoperative remifentanil consumption

Procedure: postopeartive controlled anlagesia with morphine

erector spina plane block

Active Comparator group

Description:

this group of patients received erector spina plane block preoperatively, received only postoperative patient-controlled analgesia with morphine

Treatment:

Procedure: preoperative remifentanil consumption

Procedure: postopeartive controlled anlagesia with morphine

quadratus lumborum block

Active Comparator group

Description:

this group of patients received erector spina plane block preoperatively, received only postoperative patient-controlled analgesia with morphine

Treatment:

Procedure: preoperative remifentanil consumption

Procedure: postopeartive controlled anlagesia with morphine