Comparison of Postoperative QoR-15 Scores Between Sevoflurane and Remimazolam

Yonsei University Health System (YUHS)

Status

Completed

Conditions

Anterior Cervical Discectomy and Fusion (ACDF) Surgery

Treatments

Drug: Sevoflurane based inhalation anesthesia

Drug: Remimazolam based total intravenous anesthesia

Study type

Interventional

Funder types

Other

Identifiers

NCT05019222

3-2021- 0257

Details and patient eligibility

About

The purpose of the study is to compare the quality of recovery (QoR)-15 scores according to the use of maintenance anesthetics in the cervical spine surgery. Total intravenous anesthesia (TIVA) have been known to help reducing risks of postoperative nausea/vomiting and malignant hyperthermia. However, it is still not enough to explain which is better between TIVA or inhalation anesthesia. In particular, there is no study to investigate overall postoperative functional recovery via QoR-15 in patients receiving TIVA with remimazolam. The hypothesis of the investigators study is that, in patients with cervical spine surgery, total intravenous anesthesia based on remimazolam can improve the the quality of recovery compared to inhalation anesthesia based on sevoflurane.

Enrollment

72 patients

Sex

All

Ages

20 to 70 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Adult patients who aged 20-70 years
ASA-PS: 1-3
BMI < 30
Anterior cervical discectomy and fusion surgery

Exclusion criteria

Tolerance or hypersensitivity to benzodiazepine
Dependence or addiction to psychotropic drugs or alcohol
Pregnant women, subjects who lack the ability to make decisions and susceptible to voluntary participation decisions