Comparison of Pre-hospital and In-hospital Iv-tPA Stroke Treatment

Charité University Medicine Berlin

Status: Completed

Conditions: Ischemic Stroke

Treatments: Other: thrombolysis in a pre-hospital setting (STEMO concept)

Study type: Observational

Funder types: Other

Identifiers

NCT02358772

STEMO_Outcome Analysis

Details and patient eligibility

About

This is a comparison of clinical outcomes between a pre-hospital and an in-hospital thrombolysis patient registry.

Enrollment: 658 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acute ischemic stroke diagnosis with thrombolytic treatment
• Admission via EMS
• Known premorbid status of need of assistance
• NIHSS before treatment available
• Time of onset (or last well seen) between 4:00am and 10:30pm

Exclusion criteria

• Unknown time of onset
• In-hospital thrombolysis despite decision against treatment because of contraindications in STEMO

Trial design

658 participants in 2 patient groups

Pre-hospital thrombolysis

Description:

Patients with acute ischemic stroke who are cared in a specialized STroke Emergency MObile (STEMO) before admission to the Hospital and receive thrombolytic therapy (either in STEMO or in Hospital).

Treatment:

Other: thrombolysis in a pre-hospital setting (STEMO concept)

In-hospital thrombolysis

Description:

Patients with acute ischemic stroke who receive thrombolytic therapy after admission to an University Hospital.