Comparison of Pressure-, Flow- and Neurally Adjusted Ventilatory Assistance (NAVA)-Triggering in Pediatric and Neonatal Ventilatory Care

University of Oulu

Status: Completed

Conditions: Respiration

Treatments: Device: Triggering method of the ventilator; Device: Triggering mode of the ventilator

Study type: Interventional

Funder types: Other

Identifiers

NCT00893087

EETTMK:122/2008

Details and patient eligibility

About

The purpose of this study is to study whether neurally adjusted ventilatory assist (NAVA) provides advantages over current methods in detecting patients own breathing efforts in pediatric and neonatal ventilatory care.

Our study hypothesis is that NAVA-technology is more accurate than currently used methods in detecting and assisting spontaneous breathing in children, and thus the patient-ventilator synchrony will improve.

Full description

Asynchrony means that the timing of support given by the ventilator is different from patients own breathing pattern. Asynchrony during ventilatory care may increase the risk for complications, make the weaning more difficult and may affect the survival rates.

In this study we will compare two currently used methods pressure- and flow-triggering with a neurally adjusted ventilatory assist in synchronization of the ventilator support with patients own efforts.

Enrollment: 18 estimated patients

Sex: All

Ages: Under 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All children born over 30 weeks of gestation needing ventilatory care

Exclusion criteria

• Craniofacial malformation which does not allow feeding tobe positioning. Critical ventilatory or perfusion problems.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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18 participants in 3 patient groups

1

Active Comparator group

Description:

Flow triggering

Treatment:

Device: Triggering mode of the ventilator

Device: Triggering method of the ventilator

Device: Triggering method of the ventilator

Device: Triggering method of the ventilator

2

Active Comparator group

Description:

Pressure triggering

Treatment:

Device: Triggering mode of the ventilator

Device: Triggering method of the ventilator

Device: Triggering method of the ventilator

Device: Triggering method of the ventilator

3

Active Comparator group

Description:

NAVA triggering

Treatment:

Device: Triggering mode of the ventilator

Device: Triggering method of the ventilator

Device: Triggering method of the ventilator

Device: Triggering method of the ventilator