Comparison of Prilosec OTC® Versus Zegerid® for Gastric Acid Suppression

Procter & Gamble (P&G)

Status and phase: Completed; Phase 4

Conditions: Normal Healthy Subject Population

Treatments: Drug: Zegerid®; Drug: Prilosec OTC®

Study type: Interventional

Funder types: Industry

Identifiers

NCT00808769

2008122

Details and patient eligibility

About

The purpose of this study is to compare Prilosec OTC® and Zegerid® in their effects on gastric acid suppression.

Enrollment: 30 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Normal subjects who are 18-65 years of age;
• Non-childbearing potential females or those using birth control

Exclusion criteria

• History of significant GI disease
• Any significant medical illness
• History of hypersensitivity, allergy or intolerance to omeprazole or other proton pump inhibitors;
• Currently using GI medications
• GI disorder or surgery leading to impaired drug absorption

Trial design

30 participants in 2 patient groups

1

Active Comparator group

Description:

Zegerid®

Treatment:

Drug: Zegerid®

2

Experimental group

Description:

Prilosec OTC®

Treatment:

Drug: Prilosec OTC®