Comparison of Procedural Sequences in Same-day Painless Bidirectional Endoscopy With Colonoscopic Water Exchange Method

Dalin Tzu Chi General Hospital

Status: Completed

Conditions: Colon Disease; Bidirectional Endoscopy

Treatments: Behavioral: colonoscopy first; Behavioral: EGD first

Study type: Interventional

Funder types: Other

Identifiers

NCT03638713

A10604001

Details and patient eligibility

About

This prospective randomized controlled trial is to compare evaluate the optimal procedure sequence among patients undergoing water exchange colonoscopy.

Full description

Same-day esophagogastroduodenoscopy (EGD) and colonoscopy (bidirectional endoscopy; BDE) are commonly performed to evaluate for gastrointestinal conditions, such as active gastrointestinal bleeding, iron deficiency anemia, positive fecal occult blood tests and abdominal pain. EGD-colonoscopy sequence seems to be the reasonable choice for BDE using air or CO2. With the use of water exchange method, endoscopists have to remove the dirty fecal material and air bubble during insertion. Gas insufflated during EGD may get into the colon and make subsequent water exchange colonoscopy more difficult. The aim of this prospective randomized controlled trial is to compare evaluate the optimal procedure sequence among patients undergoing water exchange colonoscopy.

Enrollment: 200 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients underwent fully sedated bidirectional endoscopy in the physical check-up department

Exclusion criteria

• Patients who < 18 years old, > 80 years old
• Without standard colon preparation
• Allergy to meperidine or propofol
• With a history of partial colectomy
• Refusal to provide written informed consent
• American Society of Anesthesiology (ASA) risk Class 3 or higher

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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200 participants in 2 patient groups

colonoscopy first group

Experimental group

Description:

Patients received water-exchange colonoscopy first and followed by esophagogastroduodenoscopy

Treatment:

Behavioral: colonoscopy first

EGD first group

Active Comparator group

Description:

Patients received esophagogastroduodenoscopy first and followed by water-exchange colonoscopy

Treatment:

Behavioral: EGD first