Comparison of Prophylactic Clip and Detachable Snare

The Catholic University of Korea

Status: Completed

Conditions: Colonic Polyp

Treatments: Procedure: Detachable snare; Procedure: Prophylactic clip

Study type: Interventional

Funder types: Other

Identifiers

NCT01406379

Prophylatic clip

Details and patient eligibility

About

Although endoscopic colonic polypectomy has been an established procedure for two decades, the risk of bleeding is still higher after resecting of pedunculated polyps, because of the presence of a large artery in the stalk. Several preventive methods such as detachable snare and adrenaline injection have been proposed in the management of postpolypectomy bleeding in large colonic polyps. For prophylactic clip, there was no prospective randomized study assessing the efficacy in the prevention of postpolypectomy bleeding for the large pedunculated polyps. So we designed a prospective, randomized study to compares the efficacy of application of prophylactic clip and detachable snare in the prevention of postpolypectomy bleeding in large polyps. Application of prophylactic clip will be as effective and safe method as detachable snare in the prevention of postpolypectomy bleeding for the large pedunculated colonic polyps.

Enrollment: 203 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with pedunculated colorectal polyps, the heads of which were larger than 10mm and the stalk of which were large than 5 mm in diameter, were included.

Exclusion criteria

• bleeding tendency
• poor preparation
• sessile polyp

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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203 participants in 2 patient groups

Prophylactic clip

Experimental group

Description:

Prophylactic clip

Treatment:

Procedure: Prophylactic clip

Detachable snare

Active Comparator group

Description:

Detachable snare

Treatment:

Procedure: Detachable snare