Comparison of PRS According to Inhalation Agent During LDLT

Seoul National University

Status and phase: Completed; Phase 4

Conditions: Liver Transplantation; Postreperfusion Syndrome

Treatments: Drug: Desflurane; Drug: sevoflurane

Study type: Interventional

Funder types: Other

Identifiers

NCT01886664

Des vs Sevo PRS

Details and patient eligibility

About

The investigators tried to evaluate the effect of desflurane on the incidence of postreperfusion syndrome during living donor liver transplantation surgery. The investigators used sevoflurane as a comparison.

Enrollment: 70 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• elective LDLT

Exclusion criteria

• age < 18, age > 65
• patient refusal
• re-transplantation

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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70 participants in 2 patient groups

Sevoflurane

Active Comparator group

Description:

Performing liver transplantation under general anesthesia using sevoflurane

Treatment:

Drug: sevoflurane

Desflurane

Experimental group

Description:

Performing liver transplantation under general anesthesia using desflurane

Treatment:

Drug: Desflurane