Comparison of Quadratus Lumborum and Combined Groin Nerve Blocks for Postoperative Analgesia After Open Inguinal Hernia Repair.

Al-Azhar University

Status and phase: Not yet enrolling; Phase 3

Conditions: Postoperative Analgesia of Inguinal Hernia Repair in Adults

Treatments: Procedure: Combined ilio-inguinal/ilio-hypogastric/genitofemoral (II-IH-GFN) block; Procedure: Ultrasound-guided lateral quadratus lumborum block

Study type: Interventional

Funder types: Other

Identifiers

NCT07343570

RC. 12.9.2025

Details and patient eligibility

About

This double-blind randomized controlled trial aimes to compares two ultrasound-guided regional techniques-lateral quadratus lumborum block versus combined ilio-inguinal/ilio-hypogastric/genitofemoral (II-IH-GFN) block-for postoperative analgesia after elective unilateral open inguinal hernia repair under spinal anesthesia in adults.

Enrollment: 66 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults aged 18-75 years.
• ASA physical status I-III.
• Scheduled for elective unilateral open inguinal hernia repair under standardized spinal anesthesia.
• Able to understand and use the Visual Analogue Scale (VAS).
• Provided written informed consent.

Exclusion criteria

• Allergy to local anesthetics.
• Coagulopathy or current use of anticoagulants contraindicating peripheral nerve blocks.
• Infection at the injection site.
• Chronic opioid use (daily opioids >2 weeks) or chronic pain syndromes.
• Body mass index (BMI) >40 kg/m².
• Conversion to other surgery or bilateral repair.
• Pregnant patients.
• Refusal to sign informed consent.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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66 participants in 2 patient groups

Group 1 (Quadratus lumborum block)

Active Comparator group

Description:

Ultrasound-guided lateral quadratus lumborum block. Local anesthetic: 30 ml of (Ropivacaine 0.2%) is injected at the appropriate fascial level.

Treatment:

Procedure: Ultrasound-guided lateral quadratus lumborum block

Group 2 ( Ilio-inguinal and ilio-hypogastric block)

Active Comparator group

Description:

Ultrasound-guided ilio-inguinal and ilio-hypogastric block. Local anesthesia: 20 ml of 0.2% ropivacaine for ilio-inguinal and ilio-hypogastric block + 10 ml of 0.2% ropivacaine for genitofemoral anaesthesia, total injection volume = 30 ml.

Treatment:

Procedure: Combined ilio-inguinal/ilio-hypogastric/genitofemoral (II-IH-GFN) block