Comparison of Quadratus Lumborum Block and Epidural Analgesia Following Kidney Transplant Surgery

University of Indonesia (UI)

Status: Completed

Conditions: Postoperative Pain

Treatments: Procedure: Continuous Epidural analgesia; Procedure: Bilateral Quadratus Lumborum block

Study type: Interventional

Funder types: Other

Identifiers

NCT03771339

IndonesiaUAnes030

Details and patient eligibility

About

Quadratus lumborum block as an alternative for postoperative analgesia compared with epidural block

Full description

Epidural analgesia is the main choice of analgesia following kidney transplant surgery. However, continuous epidural technique had some concerning side effects such as hemodynamic instabilities, urine retention, motor/sensory disturbances/weakness, and mobilisation comfort, it could also cause hypotension which could affect graft success. Quadratus lumborum (QL) block had lesser side effects thus could be an option for postoperative analgesia, however there are no study showing the safety and success rate of QL block techniques for patients who underwent kidney transplant surgery.

Enrollment: 50 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients undergoing elective kidney transplant laparotomy surgery
• Agrees to participate in research
• BMI < 30 kg/m2

Exclusion criteria

• Declines to participate in research
• Contraindications to intervention procedures (epidural or quadratus lumborum block)
• History of local anaesthetic allergy
• Systemic allergic reactions, anaphylactic reaction, cardiac arrest
• Failure of intervention procedures (epidural or quadratus lumborum block)
• Intraoperative complications (massive bleeding, hypotension)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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50 participants in 2 patient groups

Continuous Epidural Analgesia

Active Comparator group

Description:

Continuous epidural analgesia using ropivacaine 0.375% 3 mL boluses followed by ropivacaine 0.2% with rate 6 mL per hour for 24 hours

Treatment:

Procedure: Continuous Epidural analgesia

Bilateral Quadratus Lumborum Block

Experimental group

Description:

Bilateral Quadratus lumborum block using ropivacaine 0.2% 20 mL each injection after surgery

Treatment:

Procedure: Bilateral Quadratus Lumborum block