Comparison of Quadratus Lumborum Block and Erector Spina Plane Block in Nephrectomy

Eskisehir Osmangazi University

Status: Completed

Conditions: Postoperative Complications; Pain, Postoperative

Treatments: Procedure: Quadratus Lumborum Block 2; Procedure: Erector Spina Plane Block

Study type: Interventional

Funder types: Other

Identifiers

NCT04459624

ESOGU 2

Details and patient eligibility

About

Postoperative pain is important due to the limitation of physical functions, delay in recovery of quality of life, long-term opiate use, length of hospital stay, increased care costs and early postoperative pain trigger chronic pain. It is associated with postoperative morbidity. Multimodal analgesia techniques with fascial plan blocks are frequently used.The investigators aimed to evaluate the effect of QLB2 and ESP on postoperative pain scores in nephrectomy surgery, total opiate consumption, initial analgesia requirement, additional analgesia consumption, patient and surgeon satisfaction.

Full description

At the end of the operation, patients will be randomly divided into 2 groups as Group E (ESP block) and Group Q (QLB). The blocks will be administered under general anesthesia in lateral position by same anesthesiologist. Group E (ESP block) will be applied 20 ml of %0.25 bupivacaine between the erector spina muscle and transverse process at the 8th thoracic level. Group Q (QLB2 block) will be applied 20 ml of %0.25 bupivacaine at lumbar interfacial triangle (LIFT). At the end of the operation, the patients with a Modified aldreate score ≥9 will be sent from the postoperative anesthesia unit. All patients will be equipped with an IV morphine patient-controlled analgesia (PCA) device. The solution will be prepared such that morphine is 0.5 mg / ml. PCA 1mg bolus dose will be delivered with 10 min lock-out time. In the postoperative period, the patient was evaluated by another researcher who blind to the groups at the 1st and 6th, 12th and 24th hours. Visual pain scores (VAS) in rest and movement, hemodynamic values, morphine consumption, initial analgesic requirement, nausea-vomiting score, ramsey sedation scale, length of hospital stay, patient and surgeon satisfaction, and postoperative complications will be recorded.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Partial or radical nephrectomy
• American Society of Anesthesiologist physical status I-III

Exclusion criteria

• Infection in the incision area
• Coagulation disorder
• Known allergy history against to the study drugs
• Lack of adequate cognitive activity in the use of patient-controlled analgesia and VAS

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Triple Blind

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40 participants in 2 patient groups

ESP block

Active Comparator group

Description:

Intervention: Erector Spina Plane Block will administer with 20 ml of % 0.25 bupivacaine

Treatment:

Procedure: Erector Spina Plane Block

QLB 2 block

Active Comparator group

Description:

Intervention: Quadratus Lumborum Block 2 will administer with 20 ml of % 0.25 bupivacaine

Treatment:

Procedure: Quadratus Lumborum Block 2