Comparison of Quadratus Lumborum Intramuscular and Transmuscular in Postoperative Pain

Udayana University

Status: Completed

Conditions: Cesarean Section Complications; Pain, Acute; Pain, Postoperative

Treatments: Other: Quadratus lumborum block after C-section surgery as postoperative pain management

Study type: Interventional

Funder types: Other

Identifiers

NCT05005871

UNUD-CTR-FK150621-001

Details and patient eligibility

About

Acute pain is reported in approximately 80% of patients undergoing postoperative care for various types of surgical procedures in the United States. Another study reported patient postoperative pain intensity with 75% with severe pain in the first 1 to 2 postoperative days and 38% reporting moderate to severe pain at 14 postoperative days. Several modalities have been used as the standard for the management of pain postoperative C-sections.

One of the postoperative analgesic modalities for SC is quadratus lumborum block (QLB). This technique has advantages in relieving postoperative pain after C-section because it is considered to be able to relieve visceral pain as well as somatic pain. The transmuscular QLB (QLBT) approach is one of the most frequently used. This technique was found to be effective with regard to the distribution of analgesics to the paravertebral spaces which is the hallmark of QLB. However, this technique was found to be difficult to perform. Difficulties were reported related to the position of the procedure i.e. lateral or sitting position.

Enrollment: 48 patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Underwent C-section with subarachnoid block
• Aged 18-35 years old.
• ASA preoperative physical status 1-2

Exclusion criteria

• Coagulopathy
• Anatomic abnormalities of the abdomen
• History of allergy to local anesthesia
• History of hyperalgesia
• History of drug abuse (sedatives, opioids, paracetamol, or other pain relievers)
• Require postoperative intensive care
• Refuse to participate in research.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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48 participants in 2 patient groups

Quadratus lumborum intramuscular block

Active Comparator group

Description:

The quadratus lumborum intramuscular block will be performed immediately at the end of the surgery. Administration of 0.4 mL of 0.25% bupivacaine will be carried out under ultrasound guidance and performed by experienced anesthesiologists.

Treatment:

Other: Quadratus lumborum block after C-section surgery as postoperative pain management

Quadratus lumborum transmucular block

Active Comparator group

Description:

The quadratus lumborum transmuscular block will be performed immediately at the end of the surgery. Administration of 0.4 mL of 0.25% bupivacaine will be carried out under ultrasound guidance and performed by experienced anesthesiologists.

Treatment:

Other: Quadratus lumborum block after C-section surgery as postoperative pain management