Comparison of Quality of Recovery Between Remimazolam and Propofol Anesthesia in Patients Undergoing Arthroscopic Meniscectomy

Yonsei University

Status: Completed

Conditions: Adult Patients 19 or Older Scheduled for Elective Arthroscopic Meniscectomy

Treatments: Drug: Propofol TIVA; Drug: Remimazolam TIVA

Study type: Interventional

Funder types: Other

Identifiers

NCT05280236

4-2021-1803

Details and patient eligibility

About

This study aims to compare quality of recovery after surgery and anesthesia between patients undergoing arthroscopic meniscectomy under general anesthesia with either propofol or remimazolam based total intravenous anesthesia. This study is a randomized trial with a 50% probability of being assigned to either group. Randomization will be done by an anesthesiologist not involved in anesthesia or postoperative outcome assessment. Patients and the investigator in charge of postoperative outcomes assessment will be blinded to group allocation.

Enrollment: 80 patients

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients 19 or older, ASA class I~III,
• scheduled for arthroscopic meniscectomy under general anesthesia and eligible for LMA use.

Exclusion criteria

• Patient refusal,
• patients unable to read consent form, active URI or uncontrolled asthma,
• pneumonia,
• history of allergies to propofol or benzodiazepines,
• decreased liver or kidney function, heart failure of ejection fraction<55%,
• pregnant or breastfeeding patients,
• history of substance abuse/addiction

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups

Propofol

Active Comparator group

Description:

Patients receiving general anesthesia with propofol-based total intravenous anesthesia

Treatment:

Drug: Propofol TIVA

Remimazolam

Experimental group

Description:

Patients receiving general anesthesia with remimazolam-based total intravenous anesthesia

Treatment:

Drug: Remimazolam TIVA