Comparison of Scalp Microbiota of the Psoriasis and Seborrheic Dermatitis Patients

Istanbul Medeniyet University

Status: Completed

Conditions: Microbial Colonization; Seborrheic Dermatitis; Psoriasis Vulgaris

Treatments: Other: Microbiota

Study type: Observational

Funder types: Other

Identifiers

NCT03807453

IstanbulMU2

Details and patient eligibility

About

A sterile swap specimen taken from the scalp of the patients with psoriasis vulgaris or seborrheic dermatitis and the volunteer control group will be examined in our study. The examples of the microbiota of the patients will be taken both the lesional scalp and the lesion-free part of the scalp. Then, the microbiota differences between the lesioned scalp and the lesion-free scalp of both groups, and the microbiome differences between the two groups and the control group will be evaluated.

Enrollment: 30 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients with scalp psoriasis
2. Patients with seborrheic dermatitis
3. Agree to participate in research 4 - Do not use any drugs for their disease topically or systemically for two months

Exclusion criteria

1. Patients who do not want to participate in the study
2. Patients with psoriasis vulgaris or seborrheic dermatitis that does not effect scalp.
3. Those with chronic diseases that may affect skin microbiome
4. Patients using antibiotics, antifungal or antiviral therapy for any reason for the last one month.
5. Patients who are using topical or systemic drugs for their illness

Trial design

30 participants in 5 patient groups

Psoriasis Vulgaris patients-Lesion

Treatment:

Other: Microbiota

Psoriasis Vulgaris patients-Lesion free

Treatment:

Other: Microbiota

Seborrheic Dermatitis-Lesion

Treatment:

Other: Microbiota

Seborrheic Dermatitis-Lesion free

Treatment:

Other: Microbiota

Control Group

Treatment:

Other: Microbiota