Comparison of Silk Suture and Tissue Adhesive for Wound Closure After Impacted Tooth

Yuzuncu Yıl University

Status: Completed

Conditions: Tooth, Impacted; Tooth Diseases

Treatments: Procedure: Surgery of impacted mandibular wisdom teeth (the other side); Procedure: Surgery of impacted mandibular wisdom teeth

Study type: Interventional

Funder types: Other

Identifiers

NCT06112366

YYU-04/05.18.2022

Details and patient eligibility

About

This study was administered to 21 female and 9 male patients. Patients with impacted wisdom teeth on both sides of the mandible were selected. After extraction of the impacted teeth, silk sutures were used on one side and cyanoacrylate tissue adhesive on the other side for wound closure. The effects of these two materials on patient comfort were investigated.

Full description

The aim of this study was to compare the effectiveness of tissue adhesive (Periacryl 90) and silk suture in bilateral mandibular impacted wisdom tooth surgery. In the study of 30 patients, 21 females and 9 males, 60 fully impacted lower wisdom teeth were extracted bilaterally and in the same position. One of the bilaretal teeth of the patients was randomly selected and tissue adhesive (Periacryl 90) was applied for wound closure as the experimental group, while the other tooth was selected as the control group and the wound was closed with silk suture. The selected side was determined by a closed envelope procedure. After the first impacted tooth extraction, the patient waited until the wound healed and the symptoms disappeared completely, and then the other tooth was extracted. Both extractions were evaluated on days 3 and 7 for wound healing, edema and trismus. Wound healing was evaluated as good, acceptable and poor. VAS (Visual Analog Scale) was used for pain assessment

Enrollment: 30 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Volunteers with bilateral fully impacted mandibular wisdom teeth

Exclusion criteria

• Patients were excluded from the study if they did not understand the clinical procedures of the study,
• Had allergies or intolerance to any of the substances used in the study,
• Patients on anticoagulant or psychiatric treatment,
• Pregnant or breastfeeding,
• Patients using oral contraceptiveswere,
• Diabetic,
• Patients with periodontal disease or active infection,
• Poor oral hygiene

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

---

30 participants in 2 patient groups, including a placebo group

The study group used tissue adhesive for wound closure after extraction of impacted wisdom teeth

Experimental group

Description:

In this study of 30 patients, 21 females and 9 males, 60 fully impacted lower wisdom teeth were extracted bilaterally and in the same position. One of the bilaretal teeth of the patients was randomly selected and tissue adhesive (Periacryl 90) was applied for wound closure as an experimental group.

Treatment:

Procedure: Surgery of impacted mandibular wisdom teeth

Control group used silk sutures after extraction of impacted wisdom teeth

Placebo Comparator group

Description:

Bilateral impacted wisdom teeth of the patients were randomly selected. After the tooth in the experimental group was extracted, the other impacted wisdom tooth was selected as the control group and silk sutures were used for wound closure.

Treatment:

Procedure: Surgery of impacted mandibular wisdom teeth (the other side)