Comparison of Skin Prick Testing Results of Local and Imported Pollen Allergen Extracts and Specific IgE

Mahidol University

Status: Completed

Conditions: Immediate Type Hypersensitivity

Treatments: Biological: Pollen sensitization

Study type: Observational

Funder types: Other

Identifiers

NCT02764827

Si246/2556

Details and patient eligibility

About

Pollen allergen extracts are prepared locally and checked for efficacy by comparison to imported allergens and specific IgE.

Full description

Skin prick test (SPT) and specific IgE (sIgE) are approved for evaluation of allergen sensitization. Local allergen extracts are cheaper and more available but need standardization. Pollen allergen extracts: Bermuda, Johnson and careless weed are locally prepared and compared mean wheal diameter of skin prick test to imported allergens and also to specific IgE.

Enrollment: 68 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Positive skin prick test to Bermuda or Johnson or careless weed

Exclusion criteria

• Chronic diseases such as heart disease, liver, renal and severe sepsis
• Severe allergic symptoms such as anaphylaxis
• Extensive skin rashes
• Pregnancy