Comparison of Small Colorectal Polyp Removal Using Cold EMR With Hot EMR

Chonnam National University

Status: Withdrawn

Conditions: Colonic Polyps

Treatments: Procedure: Cold endoscopic mucosal resection; Procedure: Hot endoscopic mucosal resection

Study type: Interventional

Funder types: Other

Identifiers

NCT03000868

CNUH-2016-252

Details and patient eligibility

About

This study evaluates the efficacy of small colorectal polyp removal using cold endoscopic mucosal resection with hot endoscopic mucosal resection. Half of the participants will receive cold endoscopic mucosal resection, while the other half will receive hot endoscopic mucosal resection.

Full description

Colorectal polyps are considered as precancerous lesions and endoscopical resection is currently the treatment of choice when it is possible.

Colorectal polyps are classified into diminutive polyps (<5mm in diameter), small polyps (6-9mm in diameter), and large polyps (>1cm in diameter). There are several endoscopical treatment methods: cold biopsy forceps polypectomy, cold snare polypectomy, hot biopsy forceps polypectomy, hot snare polypectomy, and endoscopic mucosal resection. Cold polypectomy means mechanical removal of the polyp with snare or biopsy forceps without the use of electrocautery, and hot polypectomy means removal of the polyp with the use of electocautery.

Sex: All

Ages: 19+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with colorectal polyps that are <1cm in diameter who need endoscopic mucosal resection.

  • Patients who gave informed consents to this study.

Exclusion criteria

• Patients under the age of 19
• Patients who are receiving antiplatelet or anticoagulant therapies
• Patients with hypercoagulability (i.e., liver cirrhosis, hemophilia, end-stage renal disease, or chronic kidney disease)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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0 participants in 2 patient groups

Cold EMR group

Experimental group

Description:

Patients who have small colorectal polyps (\<1cm) who receive endoscopic mucosal resection using snare without electrocautery.

Treatment:

Procedure: Cold endoscopic mucosal resection

Hot EMR group

Active Comparator group

Description:

Patients who have small colorectal polyps (\<1cm) who receive endoscopic mucosal resection using snare with the use of electrocautery.

Treatment:

Procedure: Hot endoscopic mucosal resection