Comparison of Spinal Anesthesia Adjuvant and Quadratus Lumborum Block on the Opioid Requirement and Perioperative Pain of Laparoscopic Kidney Transplant Donor

University of Indonesia (UI)

Status: Enrolling

Conditions: Laparoscopic Donor Nephrectomy; Perioperative Pain Management

Treatments: Procedure: General Anesthesia; Procedure: Spinal anesthesia adjuvant; Procedure: Quadratus Lumborum Block (QLB)

Study type: Interventional

Funder types: Other

Identifiers

NCT06764667

IndonesiaUAnes048

Details and patient eligibility

About

This study aims to compare the effectiveness of spinal anesthesia adjuvant and quadratus lumborum block on the opioid requirement and perioperative pain on patients undergoing laparoscopic kidney transplant donor.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 18-65 years undergoing laparoscopic donor nephrectomy
• Patients with BMI ≤ 35 kg/m2
• Patients with American Society of Anesthesiology (ASA) physical status 1-2
• Patients who are willing to participate in this study

Exclusion criteria

• Cardiovascular disease (uncontrolled stage 2 hypertension, heart failure, arrhytmia)
• Recent onset cerebrovascular diseasae of < 3 months
• Infection on spinal site
• Coagulopathy
• Elevated intracranial pressure
• Severe renal or liver dysfunction
• Valvular heart disease or atrioventricular block

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Quadratus lumborum block

Active Comparator group

Description:

Patients in this arm will receive quadratus lumborum block with 20-30 ml of 0.25% Bupivacaine after induction of anesthesia and after operation.

Treatment:

Procedure: Quadratus Lumborum Block (QLB)

Procedure: General Anesthesia

Spinal anesthesia adjuvant

Experimental group

Description:

Patients in this arm will receive 10 mg 0.5% hyperbaric Bupivacaine, 100 mcg Morphine, 100 mcg Sulfas Atropine, and 0.9% normal saline to total volume of 4 ml before induction of anesthesia.

Treatment:

Procedure: Spinal anesthesia adjuvant

Procedure: General Anesthesia