Comparison of SRK-T With Kane Formula for Prediction of Refractive Outcome After Phacoemulsification

Foundation University Islamabad

Status: Completed

Conditions: Cataract; Surgery; Phacoemulsification; Biometry; Intraocular Lens Power

Treatments: Other: Biometry with Kane formula; Other: Biometry with SRK-T formula

Study type: Interventional

Funder types: Other

Identifiers

NCT05564455

FUI/CTR/2022/10

Details and patient eligibility

About

Cataract is a leading cause of blindness in the world. Cataract surgery is one of the most commonly performed ocular procedures. We aim to compare the newer generation biometry formula; the Kane formula with the commonly used SRK-T formula for intraocular power calculation in uneventful phacoemulsification surgery to assess the post-operative refractive outcomes at one month post-surgery.

Full description

Purpose: To compare post-operative refractive outcome with Sanders Retzlaff Kraff theoretical (SRK T) and Kane formulae for intraocular lens (IOL) power calculation in cataract patients Study Design: Prospective, interventional study Place and Duration of Study: Department of Ophthalmology, Fauji Foundation Hospital, Rawalpindi Material and Methods: A total of a 70 eyes, 35 in each group will be included in our study. The patients will be randomly divided into two groups. In cases of bilateral cataract, one eye will be included in each group for better control. IOL power calculation in Group A will be done with the SRK-T formula and in group 2 with the Kane Formula. Autokeratometry and A-scan ultrasound will be done for biometry. Inclusion criteria will be uncomplicated cataract in both genders. Exclusion criteria will be ocular trauma, uveitis, previous intraocular surgery, or any retinopathy. All patients will undergo phacoemulsification with foldable lens implantation by two experienced surgeons. Post-operative refractive outcome will be evaluated at one month after surgery. The two groups will be compared.

Results: The results will be calculated by SPSS. Conclusion: A conclusion will be drawn on the basis of our results.

Enrollment: 70 patients

Sex: All

Ages: 40 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Senile cataract (nuclear, cortical, posterior subcapsular, mature, hypermature cataract)
• Absence of other ocular pathology causing diminished visual acuity
• patients above 40 years of age
• Astigmatism > 2.5 diopters

Exclusion criteria

• Retinal diseases
• Maculopathy
• Uveitis
• Complications during phacoemulsification
• Combined procedures
• Previous ocular surgery
• Trauma
• Secondary cataract

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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70 participants in 2 patient groups

SRK-T Formula for Prediction of refraction

Active Comparator group

Description:

To compare post-operative refractive outcome with Sanders Retzlaff Kraff theoretical (SRK T) and Kane formulae for intraocular lens (IOL) power calculation in cataract patients

Treatment:

Other: Biometry with SRK-T formula

Kane Formula for Prediction of refraction

Active Comparator group

Description:

To compare post-operative refractive outcome with Sanders Retzlaff Kraff theoretical (SRK T) and Kane formulae for intraocular lens (IOL) power calculation in cataract patients

Treatment:

Other: Biometry with Kane formula