Comparison of Sublingual Misoprostol and Intravenous Oxytocin in Active Management of the Third Stage of Labor

Rasha Mohammed Mohammed Badawi

Status: Unknown

Conditions: Postpartum Hemorrhage Prevention by Using Oxytocin Verses Misoprostol

Study type: Observational

Funder types: Other

Identifiers

NCT01612390

hit 1234

Details and patient eligibility

About

Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor

Full description

Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor as The data from a pharmacokinetics study suggested that the bioavaiblitiy of misoprostol after sub-lingual administration was higher than those after oral or vaginal administration

Enrollment: 180 estimated patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women with aheathy singleton pregnancy in spontaneous or induced labor at term .

Exclusion criteria

• Hypersensitivity/Contraindication to prostaglandins Antepartum hemorrhage Multiple pregnancy Cardiac disease Malpresentation Rhesus- negative mother hypersensitive disorders Severe anaemia(hemoglobin<7g/dl)

Trial design

180 participants in 3 patient groups

group 1

Description:

receive 400 Mg sublingual misoprostol.

group 2

Description:

receive 600 Mg sublingual misoprostol.

group 3

Description:

receive 5IU of intravenous oxytocin.